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EZH2-mediated H3K27me3 is a predictive biomarker and therapeutic target in uveal melanoma

Although gene mutations and aberrant chromosomes are associated with the pathogenesis and prognosis of uveal melanoma (UM), potential therapeutic targets still need to be explored. We aim to determine the predictive value and potential therapeutic target of EZH2 in uveal melanoma. Eighty-five uveal...

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Detalles Bibliográficos
Autores principales: Hou, Chen, Xiao, Lirong, Ren, Xiang, Cheng, Lin, Guo, Bo, Zhang, Meixia, Yan, Naihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582331/
https://www.ncbi.nlm.nih.gov/pubmed/36276954
http://dx.doi.org/10.3389/fgene.2022.1013475