Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission

Inhibitor-2 (I-2) is a prototypic inhibitor of protein phosphatase-1 (PP1), a major serine-threonine phosphatase that regulates synaptic plasticity and learning and memory. Although I-2 is a potent inhibitor of PP1 in vitro, our previous work has elucidated that, in vivo, I-2 may act as a positive r...

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Detalles Bibliográficos
Autores principales: Foley, Karl, Altimimi, Haider, Hou, Hailong, Zhang, Yu, McKee, Cody, Papasergi-Scott, Makaía M., Yang, Hongtian, Mayer, Abigail, Ward, Nancy, MacLean, David M., Nairn, Angus C., Stellwagen, David, Xia, Houhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582336/
https://www.ncbi.nlm.nih.gov/pubmed/36276179
http://dx.doi.org/10.3389/fnsyn.2022.1021832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582336/
https://www.ncbi.nlm.nih.gov/pubmed/36276179
http://dx.doi.org/10.3389/fnsyn.2022.1021832

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