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FGF1 protects FGFR1-overexpressing cancer cells against drugs targeting tubulin polymerization by activating AKT via two independent mechanisms

Cancer drug resistance is a common, unpredictable phenomenon that develops in many types of tumors, resulting in the poor efficacy of current anticancer therapies. One of the most common, and yet the most complex causes of drug resistance is a mechanism related to dysregulation of tumor cell signali...

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Detalles Bibliográficos
Autores principales: Szymczyk, Jakub, Sochacka, Martyna, Chudy, Patryk, Opalinski, Lukasz, Otlewski, Jacek, Zakrzewska, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582358/
https://www.ncbi.nlm.nih.gov/pubmed/36276073
http://dx.doi.org/10.3389/fonc.2022.1011762