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Impact of cryopreservation on CAR T production and clinical response

Adoptive cell therapy with chimeric antigen receptor (CAR) T cells has become an efficient treatment option for patients with hematological malignancies. FDA approved CAR T products are manufactured in centralized facilities from fresh or frozen leukapheresis and the cryopreserved CAR T infusion pro...

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Detalles Bibliográficos
Autores principales: Brezinger-Dayan, Karin, Itzhaki, Orit, Melnichenko, Jenny, Kubi, Adva, Zeltzer, Li-at, Jacoby, Elad, Avigdor, Abraham, Shapira Frommer, Ronnie, Besser, Michal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582437/
https://www.ncbi.nlm.nih.gov/pubmed/36276077
http://dx.doi.org/10.3389/fonc.2022.1024362