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Frequency of Mismatch Repair Deficiency/High Microsatellite Instability and Its Role as a Predictive Biomarker of Response to Immune Checkpoint Inhibitors in Gynecologic Cancers

PURPOSE: This study was to investigate the frequency of mismatch repair deficiency/high microsatellite instability (MMRd/MSI-H) in gynecologic malignancies and the efficacy of immune checkpoint inhibitors (ICIs) in patients with recurrent gynecologic cancers according to MMR/MSI status. MATERIALS AN...

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Detalles Bibliográficos
Autores principales: Noh, Joseph J., Kim, Min Kyu, Choi, Min Chul, Lee, Jeong-Won, Park, Hyun, Jung, Sang Geun, Joo, Won Duk, Song, Seung Hun, Lee, Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582475/
https://www.ncbi.nlm.nih.gov/pubmed/34902958
http://dx.doi.org/10.4143/crt.2021.828