Cargando…

DNA damage checkpoint execution and the rules of its disengagement

Chromosomes are susceptible to damage during their duplication and segregation or when exposed to genotoxic stresses. Left uncorrected, these lesions can result in genomic instability, leading to cells’ diminished fitness, unbridled proliferation or death. To prevent such fates, checkpoint controls...

Descripción completa

Detalles Bibliográficos
Autores principales: Yam, Candice Qiu Xia, Lim, Hong Hwa, Surana, Uttam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582513/
https://www.ncbi.nlm.nih.gov/pubmed/36274841
http://dx.doi.org/10.3389/fcell.2022.1020643