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DNA damage checkpoint execution and the rules of its disengagement
Chromosomes are susceptible to damage during their duplication and segregation or when exposed to genotoxic stresses. Left uncorrected, these lesions can result in genomic instability, leading to cells’ diminished fitness, unbridled proliferation or death. To prevent such fates, checkpoint controls...
Autores principales: | Yam, Candice Qiu Xia, Lim, Hong Hwa, Surana, Uttam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582513/ https://www.ncbi.nlm.nih.gov/pubmed/36274841 http://dx.doi.org/10.3389/fcell.2022.1020643 |
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