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Evaluation of allogeneic and autologous membrane-bound IL-21–expanded NK cells for chronic lymphocytic leukemia therapy

Successes with anti-CD20 antibodies in chronic lymphocytic leukemia (CLL) and enhanced activity of Fc-engineered vs unmodified antibody therapy suggest a potentially impactful role for natural killer (NK) cells and other innate immune cells in controlling this disease. Stimulated NK cells have shown...

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Detalles Bibliográficos
Autores principales: Yano, Max, Sharpe, Chia, Lance, J. Rachel, Ravikrishnan, Janani, Zapolnik, Kevan, Mo, Xiaokui, Woyach, Jennifer A., Sampath, Deepa, Kittai, Adam S., Vasu, Sumithira, Bhat, Seema, Rogers, Kerry A., Lee, Dean A., Muthusamy, Natarajan, Byrd, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582588/
https://www.ncbi.nlm.nih.gov/pubmed/35486482
http://dx.doi.org/10.1182/bloodadvances.2021005883