Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent in primary hepatocytes

A number of G protein-coupled receptors (GPCRs) are now thought to use endocytosis to promote cellular cAMP signaling that drives downstream transcription of cAMP-dependent genes. We tested if this is true for the glucagon receptor (GCGR), which mediates physiological regulation of hepatic glucose m...

Descripción completa

Detalles Bibliográficos
Autores principales: Cajulao, Jan Mikhale B., Hernandez, Eduardo, von Zastrow, Mark E., Sanchez, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582622/
https://www.ncbi.nlm.nih.gov/pubmed/35767325
http://dx.doi.org/10.1091/mbc.E21-09-0430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582622/
https://www.ncbi.nlm.nih.gov/pubmed/35767325
http://dx.doi.org/10.1091/mbc.E21-09-0430

Ejemplares similares