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Nanotopography modulates cytoskeletal organization and dynamics during T cell activation

Exposure to MHC-antigen complexes on the surface of antigen-presenting cells (APCs) activates T cells, inducing the formation of the immune synapse (IS). Antigen detection at the APC surface is thus a critical step in the adaptive immune response. The physical properties of antigen-presenting surfac...

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Detalles Bibliográficos
Autores principales: Wheatley, Brittany A., Rey-Suarez, Ivan, Hourwitz, Matt J., Kerr, Sarah, Shroff, Hari, Fourkas, John T., Upadhyaya, Arpita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582624/
https://www.ncbi.nlm.nih.gov/pubmed/35830602
http://dx.doi.org/10.1091/mbc.E21-12-0601