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Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1

The high-affinity immunoglobulin E (IgE) receptor, FcεRI, is the primary immune receptor found on mast cells and basophils. Signal initiation is classically attributed to phosphorylation of FcεRI β− and γ-subunits by the Src family kinase (SFK) Lyn, followed by the recruitment and activation of the...

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Detalles Bibliográficos
Autores principales: Kanagy, William K., Cleyrat, Cédric, Fazel, Mohamadreza, Lucero, Shayna R., Bruchez, Marcel P., Lidke, Keith A., Wilson, Bridget S., Lidke, Diane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582627/
https://www.ncbi.nlm.nih.gov/pubmed/35793126
http://dx.doi.org/10.1091/mbc.E21-12-0603