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Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1
The high-affinity immunoglobulin E (IgE) receptor, FcεRI, is the primary immune receptor found on mast cells and basophils. Signal initiation is classically attributed to phosphorylation of FcεRI β− and γ-subunits by the Src family kinase (SFK) Lyn, followed by the recruitment and activation of the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582627/ https://www.ncbi.nlm.nih.gov/pubmed/35793126 http://dx.doi.org/10.1091/mbc.E21-12-0603 |