Cargando…

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling

During mitosis, unattached kinetochores in a dividing cell activate the spindle assembly checkpoint (SAC) and delay anaphase onset by generating the anaphase-inhibitory mitotic checkpoint complex (MCC). These kinetochores generate the MCC by recruiting its constituent proteins, including BubR1. In p...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Anand, Chen, Chu, Humphrey, Lauren, Tyson, John J., Joglekar, Ajit P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582629/
https://www.ncbi.nlm.nih.gov/pubmed/35767360
http://dx.doi.org/10.1091/mbc.E22-03-0085