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Nucleotide- and Protein-Dependent Functions of Actg1

Cytoplasmic β- and γ-actin proteins are 99% identical but support unique organismal functions. The cytoplasmic actin nucleotide sequences Actb and Actg1, respectively, are more divergent but still 89% similar. Actb(–/–) mice are embryonic lethal and Actb(–/–) cells fail to proliferate, but editing t...

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Detalles Bibliográficos
Autores principales: Sundby, Lauren J., Southern, William M., Hawbaker, Katelin M., Trujillo, Jesús M., Perrin, Benjamin J., Ervasti, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582642/
https://www.ncbi.nlm.nih.gov/pubmed/35594181
http://dx.doi.org/10.1091/mbc.E22-02-0054