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Implementing subtype‐specific pre‐clinical models of breast cancer to study pre‐treatment aspirin effects

BACKGORUND: Prior data suggest pre‐diagnostic aspirin use impacts breast tumour biology and patient outcome. Here, we employed faithful surgical resection models of HER2+ and triple‐negative breast cancer (TNBC), to study outcome and response mechanisms across breast cancer subtypes. METHOD: NOD/SCI...

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Detalles Bibliográficos
Autores principales: Miller, Ian S., Khan, Sonja, Shiels, Liam P., Das, Sudipto, O' Farrell, Alice C., Connor, Kate, Lafferty, Adam, Moran, Bruce, Isella, Claudio, Loadman, Paul, Conroy, Emer, Cohrs, Susan, Schibli, Roger, Kerbel, Robert S., Gallagher, William M., Marangoni, Elisabetta, Bennett, Kathleen, O' Connor, Darran P., Dwyer, Róisín M., Byrne, Annette T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582689/
https://www.ncbi.nlm.nih.gov/pubmed/35434898
http://dx.doi.org/10.1002/cam4.4756