Pan‐cancer analysis of mutations in open chromatin regions and their possible association with cancer pathogenesis

BACKGROUND: Open chromatin is associated with gene transcription. Previous studies have shown that the density of mutations in open chromatin regions is lower than that in flanking regions because of the higher accessibility of DNA repair machinery. However, in several cancer types, open chromatin r...

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Detalles Bibliográficos
Autores principales: Kikutake, Chie, Suyama, Mikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582691/
https://www.ncbi.nlm.nih.gov/pubmed/35416406
http://dx.doi.org/10.1002/cam4.4749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582691/
https://www.ncbi.nlm.nih.gov/pubmed/35416406
http://dx.doi.org/10.1002/cam4.4749

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