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Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures

Hepatitis C virus (HCV) is a major cause of liver-related diseases and hepatocellular carcinoma. The helicase domain of one of the nonstructural proteins of HCV, NS3 (nonstructural protein 3), is essential for viral replication; however, its specific biological role is still under investigation. Her...

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Detalles Bibliográficos
Autores principales: Belachew, Binyam, Gao, Jun, Byrd, Alicia K., Raney, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582721/
https://www.ncbi.nlm.nih.gov/pubmed/36108740
http://dx.doi.org/10.1016/j.jbc.2022.102486