Generation of new inhibitors of selected cytochrome P450 subtypes– In silico study

Physicochemical and pharmacokinetic compound profile has crucial impact on compound potency to become a future drug. Ligands with desired activity profile cannot be used for treatment if they are characterized by unfavourable physicochemical or ADMET properties. In the study, we consider metabolic s...

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Detalles Bibliográficos
Autores principales: Danel, Tomasz, Wojtuch, Agnieszka, Podlewska, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582735/
https://www.ncbi.nlm.nih.gov/pubmed/36284709
http://dx.doi.org/10.1016/j.csbj.2022.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582735/
https://www.ncbi.nlm.nih.gov/pubmed/36284709
http://dx.doi.org/10.1016/j.csbj.2022.10.005

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