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Generation of new inhibitors of selected cytochrome P450 subtypes– In silico study
Physicochemical and pharmacokinetic compound profile has crucial impact on compound potency to become a future drug. Ligands with desired activity profile cannot be used for treatment if they are characterized by unfavourable physicochemical or ADMET properties. In the study, we consider metabolic s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582735/ https://www.ncbi.nlm.nih.gov/pubmed/36284709 http://dx.doi.org/10.1016/j.csbj.2022.10.005 |