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Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues
Cancer cells are known to have larger nucleoli, consistent with their higher transcriptional and translational demands. Meanwhile, on stiff extracellular matrix, normal epithelial cells can exhibit genomic and proteomic mechanoactivation toward tumorigenic transformations, such as epithelial–mesench...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582805/ https://www.ncbi.nlm.nih.gov/pubmed/35830599 http://dx.doi.org/10.1091/mbc.E22-02-0070 |