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Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues

Cancer cells are known to have larger nucleoli, consistent with their higher transcriptional and translational demands. Meanwhile, on stiff extracellular matrix, normal epithelial cells can exhibit genomic and proteomic mechanoactivation toward tumorigenic transformations, such as epithelial–mesench...

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Detalles Bibliográficos
Autores principales: Flick Jaecker, Florence, Almeida, José A., Krull, Carly M., Pathak, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582805/
https://www.ncbi.nlm.nih.gov/pubmed/35830599
http://dx.doi.org/10.1091/mbc.E22-02-0070