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Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones

Extensive studies of growing axons have revealed many individual components and protein interactions that guide neuronal morphogenesis. Despite this, however, we lack any clear picture of the emergent mechanism by which this nanometer-scale biochemistry generates the multimicron-scale morphology and...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Aravind, Clarke, Akanni, McQueen, Philip, Fang, Hsiao Yu, Papoian, Garegin A., Giniger, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582807/
https://www.ncbi.nlm.nih.gov/pubmed/35857718
http://dx.doi.org/10.1091/mbc.E21-11-0535