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Polymer models reveal how chromatin modification can modulate force at the kinetochore

A key feature of chromosome segregation is the ability to sense tension between sister kinetochores. DNA between sister kinetochores must be packaged in a way that sustains tension propagation from one kinetochore to its sister, approximately 1 micron away. A molecular bottlebrush consisting of a pr...

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Detalles Bibliográficos
Autores principales: Lawrimore, Josh, de Larminat, Solenn C., Cook, Diana, Friedman, Brandon, Doshi, Ayush, Yeh, Elaine, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582808/
https://www.ncbi.nlm.nih.gov/pubmed/35704466
http://dx.doi.org/10.1091/mbc.E22-02-0041