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“Upcycling” known molecules and targets for drug-resistant TB

Despite reinvigorated efforts in Tuberculosis (TB) drug discovery over the past 20 years, relatively few new drugs and candidates have emerged with clear utility against drug resistant TB. Over the same period, significant technological advances and learnings around target value have taken place. Th...

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Detalles Bibliográficos
Autores principales: Roubert, Christine, Fontaine, Evelyne, Upton, Anna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582839/
https://www.ncbi.nlm.nih.gov/pubmed/36275029
http://dx.doi.org/10.3389/fcimb.2022.1029044