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Enhanced lipid metabolism confers the immunosuppressive tumor microenvironment in CD5-positive non-MYC/BCL2 double expressor lymphoma

Lymphoma cells expressing CD5 (CD5+) confer inferior outcome of diffuse large B-cell lymphoma (DLBCL), especially in non–MYC/BCL2 double expressor (non-DE) patients. In tumor microenvironment, CD5+ non-DE tumor revealed increased proportion of immunosuppressive M2 macrophages and enhanced pathways r...

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Detalles Bibliográficos
Autores principales: Liu, Meng-Ke, Cheng, Li-Li, Yi, Hong-Mei, He, Yang, Li, Xiao, Fu, Di, Dai, Yu-Ting, Fang, Hai, Cheng, Shu, Xu, Peng-Peng, Qian, Ying, Feng, Yan, Liu, Qian, Wang, Li, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583025/
https://www.ncbi.nlm.nih.gov/pubmed/36276140
http://dx.doi.org/10.3389/fonc.2022.885011