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The infectivity and pathogenicity of hepatitis A virus live-attenuated vaccine strain H2 in type I interferon receptor-deficient mice

Hepatitis A virus (HAV) live-attenuated vaccine H2 strain has been approved for clinical use for decades with ideal safety profiles in nonhuman primate models and humans. Recently, type I interferon (IFN) receptor-deficient mice were shown to be susceptible to HAV infection. Herein, we sought to det...

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Detalles Bibliográficos
Autores principales: Ma, Qing-Qing, Wang, Hong-Jiang, Li, Jian, Li, Meng-Qi, Cao, Tian-Shu, Wu, Xiao-Yan, Qiu, Hong-Ying, Zhao, Hui, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583102/
https://www.ncbi.nlm.nih.gov/pubmed/35863604
http://dx.doi.org/10.1016/j.virs.2022.07.009