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Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy

Galactose (Gal)-deficient IgA1 (Gd-IgA1) is involved in IgA nephropathy (IgAN) pathogenesis. To reflect racial differences in clinical characteristics, we assessed disease- and race-specific heterogeneity in the O-glycosylation of the IgA1 hinge region (HR). We determined serum Gd-IgA1 levels in Cau...

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Detalles Bibliográficos
Autores principales: Ohyama, Yukako, Yamaguchi, Hisateru, Ogata, Soshiro, Chiurlia, Samantha, Cox, Sharon N., Kouri, Nikoletta-Maria, Stangou, Maria J., Nakajima, Kazuki, Hayashi, Hiroki, Inaguma, Daijo, Hasegawa, Midori, Yuzawa, Yukio, Tsuboi, Naotake, Renfrow, Matthew B., Novak, Jan, Papagianni, Aikaterini A., Schena, Francesco P., Takahashi, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583103/
https://www.ncbi.nlm.nih.gov/pubmed/36277451
http://dx.doi.org/10.1016/j.isci.2022.105223