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Assessment of the immunogenicity and protection of a Nipah virus soluble G vaccine candidate in mice and pigs

Nipah virus (NiV) is a newly emerged extremely dangerous zoonotic pathogen highly fatal to humans. Currently, no approved vaccine is available against NiV. This study employed a mammalian eukaryotic system to express NiV soluble G glycoprotein (NiV-sG), using CpG oligodeoxynucleotides (CpG)/Aluminum...

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Detalles Bibliográficos
Autores principales: Gao, Zihan, Li, Tao, Han, Jicheng, Feng, Sheng, Li, Letian, Jiang, Yuhang, Xu, Zhiqiang, Hao, Pengfei, Chen, Jing, Hao, Jiayi, Xu, Peng, Tian, Mingyao, Jin, Ningyi, Huang, Weijin, Li, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583134/
https://www.ncbi.nlm.nih.gov/pubmed/36274696
http://dx.doi.org/10.3389/fmicb.2022.1031523