Validation of in silico biomarkers for drug screening through ordinal logistic regression

Since the Comprehensive in vitro Proarrhythmia Assay (CiPA) initiation, many studies have suggested various in silico features based on ionic charges, action potentials (AP), or intracellular calcium (Ca) to assess proarrhythmic risk. These in silico features are computed through electrophysiologica...

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Detalles Bibliográficos
Autores principales: Jeong, Da Un, Danadibrata, Rakha Zharfarizqi, Marcellinus, Aroli, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583152/
https://www.ncbi.nlm.nih.gov/pubmed/36277213
http://dx.doi.org/10.3389/fphys.2022.1009647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583152/
https://www.ncbi.nlm.nih.gov/pubmed/36277213
http://dx.doi.org/10.3389/fphys.2022.1009647

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