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The role of ubiquitination in spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a neurodegenerative and neuromuscular genetic disease caused by the expansion of a polyglutamine-encoding CAG tract in the androgen receptor (AR) gene. The AR is an important transcriptional regulator of the nuclear hormone receptor superfamily; its level...

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Detalles Bibliográficos
Autores principales: Sengupta, Medha, Pluciennik, Anna, Merry, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583669/
https://www.ncbi.nlm.nih.gov/pubmed/36277484
http://dx.doi.org/10.3389/fnmol.2022.1020143