Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors

PURPOSE: Loss of retinoschisin (RS1) function underlies X-linked retinoschisis (XLRS) pathology. In the retina, both photoreceptor inner segments and bipolar cells express RS1. However, the loss of RS1 function causes schisis primarily in the inner retina. To understand these cell type–specific phen...

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Detalles Bibliográficos
Autores principales: Vijayasarathy, Camasamudram, Zeng, Yong, Marangoni, Dario, Dong, Lijin, Pan, Zhuo-Hua, Simpson, Elizabeth M., Fariss, Robert N., Sieving, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583743/
https://www.ncbi.nlm.nih.gov/pubmed/36227606
http://dx.doi.org/10.1167/iovs.63.11.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583743/
https://www.ncbi.nlm.nih.gov/pubmed/36227606
http://dx.doi.org/10.1167/iovs.63.11.8

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