Hypoxia-Inducible Factor-1α in Rods Is Neuroprotective Following Retinal Detachment

PURPOSE: Following retinal detachment (RD) photoreceptors (PRs) sustain hypoxic stress and eventually die. Hypoxia-inducible factor-1α (HIF-1α) plays a central role in cellular adaptation to hypoxia. The purpose of this study is to determine the necessity of HIF-1α on PR cell survival after RD. METH...

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Detalles Bibliográficos
Autores principales: Ross, Bing X., Jia, Lin, Kong, Dejuan, Wang, Tiantian, Yao, Jingyu, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583748/
https://www.ncbi.nlm.nih.gov/pubmed/36223101
http://dx.doi.org/10.1167/iovs.63.11.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583748/
https://www.ncbi.nlm.nih.gov/pubmed/36223101
http://dx.doi.org/10.1167/iovs.63.11.7

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