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STAG2 Expression is Associated with Adverse Survival Outcomes and Regulates Cell Phenotype in Muscle-invasive Bladder Cancer

Stromal antigen 2 (STAG2), in healthy somatic cells, functions in sister chromatid cohesion, DNA damage repair, and genome organization, but its role in muscle-invasive bladder cancer (MIBC) remains unknown. Here, using whole-exome and targeted sequencing (n = 119 bladder cancer clinical samples), w...

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Detalles Bibliográficos
Autores principales: Athans, Sarah R., Krishnan, Nithya, Ramakrishnan, Swathi, Cortes Gomez, Eduardo, Lage-Vickers, Sofía, Rak, Monika, Kazmierczak, Zara I., Ohm, Joyce Ellen, Attwood, Kristopher, Wang, Jianmin, Woloszynska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583756/
https://www.ncbi.nlm.nih.gov/pubmed/36275363
http://dx.doi.org/10.1158/2767-9764.CRC-22-0155