Cargando…
STAG2 Expression is Associated with Adverse Survival Outcomes and Regulates Cell Phenotype in Muscle-invasive Bladder Cancer
Stromal antigen 2 (STAG2), in healthy somatic cells, functions in sister chromatid cohesion, DNA damage repair, and genome organization, but its role in muscle-invasive bladder cancer (MIBC) remains unknown. Here, using whole-exome and targeted sequencing (n = 119 bladder cancer clinical samples), w...
Autores principales: | Athans, Sarah R., Krishnan, Nithya, Ramakrishnan, Swathi, Cortes Gomez, Eduardo, Lage-Vickers, Sofía, Rak, Monika, Kazmierczak, Zara I., Ohm, Joyce Ellen, Attwood, Kristopher, Wang, Jianmin, Woloszynska, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583756/ https://www.ncbi.nlm.nih.gov/pubmed/36275363 http://dx.doi.org/10.1158/2767-9764.CRC-22-0155 |
Ejemplares similares
-
Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
por: Ramakrishnan, Swathi, et al.
Publicado: (2019) -
Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer
por: Ramakrishnan, Swathi, et al.
Publicado: (2017) -
Serum Androgen Metabolites Correlate with Clinical Variables in African and European American Men with Localized, Therapy Naïve Prostate Cancer
por: Ramakrishnan, Swathi, et al.
Publicado: (2023) -
Biological differences underlying sex and gender disparities in bladder cancer: current synopsis and future directions
por: Doshi, Bhavisha, et al.
Publicado: (2023) -
Frequent truncating mutations of STAG2 in bladder cancer
por: Solomon, David A., et al.
Publicado: (2013)