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Effect of drug-to-lipid ratio on nanodisc-based tenofovir drug delivery to the brain for HIV-1 infection

BACKGROUND: Combination antiretroviral therapy has significantly advanced HIV-1 infection treatment. However, HIV-1 remains persistent in the brain; the inaccessibility of the blood–brain barrier allows for persistent HIV-1 infections and neuroinflammation. Nanotechnology-based drug carriers such as...

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Detalles Bibliográficos
Autores principales: Garcia, Caroline R, Rad, Armin T, Saeedinejad, Farnoosh, Manojkumar, Arvind, Roy, Deepa, Rodrigo, Hansapani, Chew, Sue Anne, Rahman, Ziyaur, Nieh, Mu-Ping, Roy, Upal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583757/
https://www.ncbi.nlm.nih.gov/pubmed/35642549
http://dx.doi.org/10.2217/nnm-2022-0043