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isomiRTar: a comprehensive portal of pan-cancer 5′-isomiR targeting

Inaccurate cleavage of pri- and pre-miRNA hairpins by Drosha and Dicer results in the generation of miRNA isoforms known as isomiRs. isomiRs with 5′-end variations (5′-isomiRs) create a new dimension in miRNA research since they have different seed regions and distinct targetomes. We developed isomi...

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Detalles Bibliográficos
Autores principales: Nersisyan, Stepan, Gorbonos, Aleksandra, Makhonin, Alexey, Zhiyanov, Anton, Shkurnikov, Maxim, Tonevitsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583861/
https://www.ncbi.nlm.nih.gov/pubmed/36275459
http://dx.doi.org/10.7717/peerj.14205