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Multicomponent Pseudomonas aeruginosa Vaccines Eliciting Th17 Cells and Functional Antibody Responses Confer Enhanced Protection against Experimental Acute Pneumonia in Mice

The Gram-negative pathogen Pseudomonas aeruginosa is a common cause of pneumonia in hospitalized patients. Its increasing antibiotic resistance and widespread occurrence present a pressing need for vaccines. We previously showed that a P. aeruginosa type III secretion system protein, PopB, elicits a...

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Detalles Bibliográficos
Autores principales: Shaikh, Mohammad Omar Faruk, Schaefers, Matthew M., Merakou, Christina, DiBlasi, Marco, Bonney, Sarah, Liao, Tiffany, Zurakowski, David, Kehl, Margaret, Tabor, David E., DiGiandomenico, Antonio, Priebe, Gregory P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584304/
https://www.ncbi.nlm.nih.gov/pubmed/36069593
http://dx.doi.org/10.1128/iai.00203-22