A two–tiered system for selective receptor and transporter protein degradation

Diverse physiology relies on receptor and transporter protein down–regulation and degradation mediated by ESCRTs. Loss–of–function mutations in human ESCRT genes linked to cancers and neurological disorders are thought to block this process. However, when homologous mutations are introduced into mod...

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Detalles Bibliográficos
Autores principales: Golden, Charlotte Kathleen, Kazmirchuk, Thomas David Daniel, McNally, Erin Kate, El eissawi, Mariyam, Gokbayrak, Zeynep Derin, Richard, Joël Denis, Brett, Christopher Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584418/
https://www.ncbi.nlm.nih.gov/pubmed/36215320
http://dx.doi.org/10.1371/journal.pgen.1010446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584418/
https://www.ncbi.nlm.nih.gov/pubmed/36215320
http://dx.doi.org/10.1371/journal.pgen.1010446

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