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Experimental guidance for discovering genetic networks through hypothesis reduction on time series

Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are controlled by a relatively small “core” network of transcription factors and post-translational modifiers, working in concerted mutual regulation. Recent work suggests that system-independent, quantitative features...

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Detalles Bibliográficos
Autores principales: Cummins, Breschine, Motta, Francis C., Moseley, Robert C., Deckard, Anastasia, Campione, Sophia, Gameiro, Marcio, Gedeon, Tomáš, Mischaikow, Konstantin, Haase, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584434/
https://www.ncbi.nlm.nih.gov/pubmed/36215333
http://dx.doi.org/10.1371/journal.pcbi.1010145