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An ultra-sensitive method to detect mutations in human RAS templates
The RAS family of small GTPases is mutated in roughly a fifth of human cancers. Hotspot point mutations at codons G(12), G(13), and Q(61) account for 95% of all these mutations, which are well established to render the encoded proteins oncogenic. In humans, this family comprises three genes: HRAS, N...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584555/ https://www.ncbi.nlm.nih.gov/pubmed/35658790 http://dx.doi.org/10.1080/21541248.2022.2083895 |