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Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming

Synapses contain a limited number of synaptic vesicles (SVs) that are released in response to action potentials (APs). Therefore, sustaining synaptic transmission over a wide range of AP firing rates and timescales depends on SV release and replenishment. Although actin dynamics impact synaptic tran...

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Detalles Bibliográficos
Autores principales: Keine, Christian, Al-Yaari, Mohammed, Radulovic, Tamara, Thomas, Connon I, Valino Ramos, Paula, Guerrero-Given, Debbie, Ranjan, Mrinalini, Taschenberger, Holger, Kamasawa, Naomi, Young, Samuel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584605/
https://www.ncbi.nlm.nih.gov/pubmed/36214784
http://dx.doi.org/10.7554/eLife.81505