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Pravastatin Reduces Matrix Metalloproteinases Expression and Promotes Cholesterol Efflux in Osteoarthritis Chondrocytes

BACKGROUND: Chondrocyte metabolic disorder plays an important role in the development of osteoarthritis (OA). The use of statins in the treatment of OA has also been widely studied, but the mechanism is still confusing. The present study aims to investigate the effects of statin on osteoarthritis ch...

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Detalles Bibliográficos
Autores principales: Wu, Yunpeng, Li, Xuezhou, Guo, Yongyuan, Jia, Yuhua, Sun, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584666/
https://www.ncbi.nlm.nih.gov/pubmed/36276856
http://dx.doi.org/10.1155/2022/9666963