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Ganoderic Acid A Inhibits High Glucose-Induced Oxidative Stress and Extracellular Matrix Accumulation in Rat Glomerular Mesangial Cells

OBJECTIVE: We aimed to investigate the role of ganoderic acid A (GAA) in glomerular mesangial cells (GMCs) under high glucose (HG). METHODS: GMCs were pretreated with GAA and then cultured under HG condition for 24 h. Cell proliferation was measured by CCK-8 assay. The production of intracellular RO...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Wu, Bing, Zhu, Yanting, Jin, Gang, Fan, Xiaobao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584714/
https://www.ncbi.nlm.nih.gov/pubmed/36277981
http://dx.doi.org/10.1155/2022/5249910