COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

Mitochondrial respiratory complexes form superassembled structures called supercomplexes. COX7A2L is a supercomplex-specific assembly factor in mammals, although its implication for supercomplex formation and cellular metabolism remains controversial. Here we identify a role for COX7A2L for mitochon...

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Detalles Bibliográficos
Autores principales: Benegiamo, Giorgia, Bou Sleiman, Maroun, Wohlwend, Martin, Rodríguez-López, Sandra, Goeminne, Ludger J. E., Laurila, Pirkka-Pekka, Klevjer, Marie, Salonen, Minna K., Lahti, Jari, Jha, Pooja, Cogliati, Sara, Enriquez, José Antonio, Brumpton, Ben M., Bye, Anja, Eriksson, Johan G., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584823/
https://www.ncbi.nlm.nih.gov/pubmed/36253618
http://dx.doi.org/10.1038/s42255-022-00655-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584823/
https://www.ncbi.nlm.nih.gov/pubmed/36253618
http://dx.doi.org/10.1038/s42255-022-00655-0

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