GAB functions as a bioenergetic and signalling gatekeeper to control T cell inflammation

γ-Aminobutyrate (GAB), the biochemical form of (GABA) γ-aminobutyric acid, participates in shaping physiological processes, including the immune response. How GAB metabolism is controlled to mediate such functions remains elusive. Here we show that GAB is one of the most abundant metabolites in CD4(...

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Detalles Bibliográficos
Autores principales: Kang, Siwen, Liu, Lingling, Wang, Tingting, Cannon, Matthew, Lin, Penghui, Fan, Teresa W.-M., Scott, David A., Wu, Hsin-Jung Joyce, Lane, Andrew N., Wang, Ruoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584824/
https://www.ncbi.nlm.nih.gov/pubmed/36192601
http://dx.doi.org/10.1038/s42255-022-00638-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584824/
https://www.ncbi.nlm.nih.gov/pubmed/36192601
http://dx.doi.org/10.1038/s42255-022-00638-1

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