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GAB functions as a bioenergetic and signalling gatekeeper to control T cell inflammation
γ-Aminobutyrate (GAB), the biochemical form of (GABA) γ-aminobutyric acid, participates in shaping physiological processes, including the immune response. How GAB metabolism is controlled to mediate such functions remains elusive. Here we show that GAB is one of the most abundant metabolites in CD4(...
Autores principales: | Kang, Siwen, Liu, Lingling, Wang, Tingting, Cannon, Matthew, Lin, Penghui, Fan, Teresa W.-M., Scott, David A., Wu, Hsin-Jung Joyce, Lane, Andrew N., Wang, Ruoning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584824/ https://www.ncbi.nlm.nih.gov/pubmed/36192601 http://dx.doi.org/10.1038/s42255-022-00638-1 |
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