Cargando…

Behavioral and neurochemical interactions of the tricyclic antidepressant drug desipramine with L-DOPA in 6-OHDA-lesioned rats. Implications for motor and psychiatric functions in Parkinson’s disease

RATIONALE: The pharmacological effects of antidepressants in modulating noradrenergic transmission as compared to serotonergic transmission in a rat model of Parkinson’s disease under chronic L-DOPA therapy are insufficiently explored. OBJECTIVES: The aim of the present study was to investigate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamińska, Kinga, Lenda, Tomasz, Konieczny, Jolanta, Lorenc-Koci, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584871/
https://www.ncbi.nlm.nih.gov/pubmed/36178508
http://dx.doi.org/10.1007/s00213-022-06238-x