Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease

The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the regulation of the tumour suppressor E-cadherin. Hakai is overexpressed in colon cancer,...

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Detalles Bibliográficos
Autores principales: Roca-Lema, Daniel, Quiroga, Macarena, Khare, Vineeta, Díaz-Díaz, Andrea, Barreiro-Alonso, Aida, Rodríguez-Alonso, Andrea, Concha, Ángel, Romay, Gabriela, Cerdán, M. Esperanza, Gasche, Christoph, Figueroa, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584894/
https://www.ncbi.nlm.nih.gov/pubmed/36266428
http://dx.doi.org/10.1038/s41598-022-22295-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584894/
https://www.ncbi.nlm.nih.gov/pubmed/36266428
http://dx.doi.org/10.1038/s41598-022-22295-w

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