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Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease
The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the regulation of the tumour suppressor E-cadherin. Hakai is overexpressed in colon cancer,...
Autores principales: | Roca-Lema, Daniel, Quiroga, Macarena, Khare, Vineeta, Díaz-Díaz, Andrea, Barreiro-Alonso, Aida, Rodríguez-Alonso, Andrea, Concha, Ángel, Romay, Gabriela, Cerdán, M. Esperanza, Gasche, Christoph, Figueroa, Angélica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584894/ https://www.ncbi.nlm.nih.gov/pubmed/36266428 http://dx.doi.org/10.1038/s41598-022-22295-w |
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