Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity

Antibodies against phosphorylated alpha-synuclein (aSyn) at S129 have emerged as the primary tools to investigate, monitor, and quantify aSyn pathology in the brain and peripheral tissues of patients with Parkinson’s disease and other neurodegenerative diseases. Herein, we demonstrate that the co-oc...

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Detalles Bibliográficos
Autores principales: Lashuel, Hilal A., Mahul-Mellier, Anne-Laure, Novello, Salvatore, Hegde, Ramanath Narayana, Jasiqi, Yllza, Altay, Melek Firat, Donzelli, Sonia, DeGuire, Sean M., Burai, Ritwik, Magalhães, Pedro, Chiki, Anass, Ricci, Jonathan, Boussouf, Manel, Sadek, Ahmed, Stoops, Erik, Iseli, Christian, Guex, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584898/
https://www.ncbi.nlm.nih.gov/pubmed/36266318
http://dx.doi.org/10.1038/s41531-022-00388-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584898/
https://www.ncbi.nlm.nih.gov/pubmed/36266318
http://dx.doi.org/10.1038/s41531-022-00388-7

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