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Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function

Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains an unmet medical need despite improved therapy. This limitation likely reflects the diversity of pathogenic pathways in RA, with individual patients demonstrating variable responses to targeted therapi...

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Detalles Bibliográficos
Autores principales: Ainsworth, Richard I., Hammaker, Deepa, Nygaard, Gyrid, Ansalone, Cecilia, Machado, Camilla, Zhang, Kai, Zheng, Lina, Carrillo, Lucy, Wildberg, Andre, Kuhs, Amanda, Svensson, Mattias N. D., Boyle, David L., Firestein, Gary S., Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584907/
https://www.ncbi.nlm.nih.gov/pubmed/36266270
http://dx.doi.org/10.1038/s41467-022-33785-w